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Dyrenium (Triamterene)
Dyrenium (Triamterene)

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Dyrenium (Triamterene)

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Commercial Name: Dyrenium 
Active Ingredient: Triamterene
Production form: Pills 
Utilization: Used to treat fluid retention (oedema) and high blood pressure (hypertension)
Available Dosages: 37.5mg and 75mg
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Why is this medication prescribed?
        Triamterene is used alone or with other medications to treat oedema (fluid retention; excess fluid held in body tissues) caused by various conditions, including liver and heart disease. Triamterene is in a class of medications called diuretics ('water pills'). It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium.

How should this medicine be used?
        Triamterene comes as a capsule to take by mouth. It usually is taken once a day in the morning after breakfast or twice a day after breakfast and lunch. It is best to take triamterene earlier in the day so that frequent trips to the bathroom do not interfere with nighttime sleep. Take triamterene at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take triamterene exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Other uses for this medicine
        Triamterene is used in combination with other diuretics to treat high blood pressure.

        This medicine may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?
Before taking triamterene:
tell your doctor and pharmacist if you are allergic to triamterene or any other medications (Dyazide, Maxzide).
do not take triamterene if you are taking amiloride (Midamor), spironolactone (Aldactone), or other medications containing triamterene.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril, (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); lithium (Eskalith, Lithobid); nonsteroidal anti-inflammatory medications (NSAIDS) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); medications for diabetes, or high blood pressure; other diuretics; and potassium supplements. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have or have ever had diabetes, gout, kidney stones, or heart, kidney, or liver disease.
tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking triamterene, call your doctor. Do not breastfeed if you are taking triamterene.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking triamterene.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Triamterene may make your skin sensitive to sunlight.
What special dietary instructions should I follow?
Follow your doctor's directions for your meals, including advice for a reduced salt (sodium) diet and daily exercise program. Avoid potassium-containing salt substitutes while you are taking this medication..Talk with your doctor about the amount of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) that you may have in your diet.

What should I do if I forget a dose?
        Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?
Triamterene may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
headache Some

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
muscle weakness or cramps
slow or irregular heartbeat
difficulty breathing or swallowing
upset stomach
extreme tiredness
unusual bleeding or bruising
lack of energy
loss of appetite
pain in the upper right part of the stomach
yellowing of the skin or eyes
flu-like symptoms
sore throat
severe dry mouth
unusual bruising or bleeding

By Cathy Wong | Claudia Chaves, MD Medically reviewed by
Updated on 9.08.2022
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